ACTIVITY OF LIVER FUNCTION ENZYME AND ANTIBACTERIAL SUSCEPTIBILITY OF ANNONA SENEGALENSIS LEAF EXTRACT

In ethnomedicine, various natural products have been implicated in the treatment of several diseases. Annona senegalensis has identified as one plants that potential to cure ailments arising from microbial infections. This study however was carried out investigate liver function enzyme activity and vitro antibacterial susceptibility 50% ethanol-methanol leaf extract A. senegalensis. The effect administration 100 mg/kg body weight on serum parameters investigated albino rats. Thirty-three rats with average weights 200 g were divided into two groups. Group 1 contained 30 treated 20 mg/mL while 2 three served control. lasted for consecutive days daily administered Data analyzed presented using a descriptive analysis Microsoft Excel 2016 version. results obtained enzymes show significant increase when compared indicates extracts effects parameters. relative drugs (Ampicillin Ciprofloxacin) revealed plant holds much promise property combined antibiotics used this study. research there is high alkaline phosphatase, aspartate aminotransferase, alanine aminotransferase following test also property. combination antibiotic drugs, especially hold its efficacy synergistic interaction.